Current Understanding of the Role of Complement in IgA Nephropathy

Complement activation has a role in the pathogenesis of IgA nephropathy, an autoimmune disease mediated by pathogenic immune complexes consisting of galactose-deficient IgA1 bound by antiglycan antibodies. Of three complement-activation pathways, the alternative and lectin pathways are involved in I...

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Publicat a:J Am Soc Nephrol
Autors principals: Maillard, Nicolas, Wyatt, Robert J., Julian, Bruce A., Kiryluk, Krzysztof, Gharavi, Ali, Fremeaux-Bacchi, Veronique, Novak, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2015
Matèries:
Up Front Matters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483595/
https://ncbi.nlm.nih.gov/pubmed/25694468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014101000
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