SIRT2 Regulates LPS-Induced Renal Tubular CXCL2 and CCL2 Expression

Sirtuin 2 (SIRT2), a NAD(+)-dependent histone deacetylase, is involved in carcinogenesis and genomic instability and modulates proinflammatory immune responses. However, its role in renal inflammatory injury has not been demonstrated. In this study, we explored the expression patterns of CXCL2 and C...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Jung, Yu Jin, Lee, Ae Sin, Nguyen-Thanh, Tung, Kim, Dal, Kang, Kyung Pyo, Lee, Sik, Park, Sung Kwang, Kim, Won
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483578/
https://ncbi.nlm.nih.gov/pubmed/25349202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014030226
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