SIRT2 Regulates LPS-Induced Renal Tubular CXCL2 and CCL2 Expression

Sirtuin 2 (SIRT2), a NAD(+)-dependent histone deacetylase, is involved in carcinogenesis and genomic instability and modulates proinflammatory immune responses. However, its role in renal inflammatory injury has not been demonstrated. In this study, we explored the expression patterns of CXCL2 and C...

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Foilsithe in:J Am Soc Nephrol
Main Authors: Jung, Yu Jin, Lee, Ae Sin, Nguyen-Thanh, Tung, Kim, Dal, Kang, Kyung Pyo, Lee, Sik, Park, Sung Kwang, Kim, Won
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Nephrology 2015
Ábhair:
Basic Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483578/
https://ncbi.nlm.nih.gov/pubmed/25349202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014030226
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