Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model

Na(+) transport in the renal distal convoluted tubule (DCT) by the thiazide-sensitive NaCl cotransporter (NCC) is a major determinant of total body Na(+) and BP. NCC-mediated transport is stimulated by aldosterone, the dominant regulator of chronic Na(+) homeostasis, but the mechanism is controversi...

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Udgivet i:J Am Soc Nephrol
Main Authors: Hunter, Robert W., Ivy, Jessica R., Flatman, Peter W., Kenyon, Christopher J., Craigie, Eilidh, Mullins, Linda J., Bailey, Matthew A., Mullins, John J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2015
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483573/
https://ncbi.nlm.nih.gov/pubmed/25349206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013060634
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