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Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release

Streptococcus pneumoniae (the pneumococcus) colonizes the human nasopharynx and is a significant pathogen worldwide. Pneumolysin (Ply) is a multi-functional, extracellular virulence factor produced by this organism that is critical for pathogenesis. Despite the absence of any apparent secretion or c...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Greene, Neil G., Narciso, Ana R., Filipe, Sergio R., Camilli, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483231/
https://ncbi.nlm.nih.gov/pubmed/26114646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004996
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