Periostin is a novel therapeutic target that predicts and regulates glioma malignancy

BACKGROUND: Periostin is a secreted matricellular protein critical for epithelial-mesenchymal transition and carcinoma metastasis. In glioblastoma, it is highly upregulated compared with normal brain, and existing reports indicate potential prognostic and functional importance in glioma. However, th...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Mikheev, Andrei M., Mikheeva, Svetlana A., Trister, Andrew D., Tokita, Mari J., Emerson, Samuel N., Parada, Carolina A., Born, Donald E., Carnemolla, Barbara, Frankel, Sam, Kim, Deok-Ho, Oxford, Rob G., Kosai, Yoshito, Tozer-Fink, Kathleen R., Manning, Thomas C., Silber, John R., Rostomily, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483094/
https://ncbi.nlm.nih.gov/pubmed/25140038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou161
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