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Viral infection of implanted meningeal tumors induces antitumor memory T-cells to travel to the brain and eliminate established tumors

BACKGROUND: Leptomeningeal metastases occur in 2%–5% of patients with breast cancer and have an exceptionally poor prognosis. The blood–brain and blood–meningeal barriers severely inhibit successful chemotherapy. We have developed a straightforward method to induce antitumor memory T-cells using a H...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Gao, Yanhua, Whitaker-Dowling, Patricia, Barmada, Mamdouha A., Basse, Per H., Bergman, Ira
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483070/
https://ncbi.nlm.nih.gov/pubmed/25223975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou231
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