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Viral infection of implanted meningeal tumors induces antitumor memory T-cells to travel to the brain and eliminate established tumors
BACKGROUND: Leptomeningeal metastases occur in 2%–5% of patients with breast cancer and have an exceptionally poor prognosis. The blood–brain and blood–meningeal barriers severely inhibit successful chemotherapy. We have developed a straightforward method to induce antitumor memory T-cells using a H...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4483070/ https://ncbi.nlm.nih.gov/pubmed/25223975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou231 |
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