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Contemporary murine models in preclinical astrocytoma drug development

Despite 6 decades of research, only 3 drugs have been approved for astrocytomas, the most common malignant primary brain tumors. However, clinical drug development is accelerating with the transition from empirical, cytotoxic therapy to precision, targeted medicine. Preclinical animal model studies...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: McNeill, Robert S., Vitucci, Mark, Wu, Jing, Miller, C. Ryan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483055/
https://ncbi.nlm.nih.gov/pubmed/25246428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou288
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