A prospective open-label study of sirolimus for the treatment of anti-Hu associated paraneoplastic neurological syndromes

BACKGROUND: Several lines of evidence suggest a T cell–mediated immune response in paraneoplastic neurological syndromes with anti-Hu antibodies (Hu-PNS). In order to investigate whether suppression of T cell–mediated immune responses in Hu-PNS patients improved their neurological outcome, we perfor...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: de Jongste, Adriaan H., van Gelder, Teun, Bromberg, Jacoline E., de Graaf, Marieke T., Gratama, Jan W., Schreurs, Marco W., Hooijkaas, Herbert, Sillevis Smitt, Peter A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Clinical Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483045/
https://ncbi.nlm.nih.gov/pubmed/24994790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou126
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