Three sensitive assays do not provide evidence for circulating HuD-specific T cells in the blood of patients with paraneoplastic neurological syndromes with anti-Hu antibodies

Anti-Hu antibody–associated paraneoplastic neurological syndromes (Hu-PNSs) are severe and often precede the detection of a malignancy, usually small-cell lung cancer. In Hu-PNS, it is hypothesized that neuronal cells are destroyed by T cells targeted against HuD, a protein expressed by small-cell l...

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Autors principals: de Jongste, Adriaan H.C., de Graaf, Marieke T., Martinuzzi, Emanuela, van den Broek, Patricia D.M., Kraan, Jaco, Lamers, Cor H.J., Mallone, Roberto, Gratama, Jan W., Sillevis Smitt, Peter A.E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379804/
https://ncbi.nlm.nih.gov/pubmed/22591661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos118
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