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Individual Patient Data Analysis of Progression-Free Survival Versus Overall Survival As a First-Line End Point for Metastatic Colorectal Cancer in Modern Randomized Trials: Findings From the Analysis and Research in Cancers of the Digestive System Database

PURPOSE: Progression-free survival (PFS) has previously been established as a surrogate for overall survival (OS) for first-line metastatic colorectal cancer (mCRC). Because mCRC treatment has advanced in the last decade with extended OS, this surrogacy requires re-examination. METHODS: Individual p...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Shi, Qian, de Gramont, Aimery, Grothey, Axel, Zalcberg, John, Chibaudel, Benoist, Schmoll, Hans-Joachim, Seymour, Matthew T., Adams, Richard, Saltz, Leonard, Goldberg, Richard M., Punt, Cornelis J.A., Douillard, Jean-Yves, Hoff, Paulo M., Hecht, Joel Randolph, Hurwitz, Herbert, Díaz-Rubio, Eduardo, Porschen, Rainer, Tebbutt, Niall C., Fuchs, Charles, Souglakos, John, Falcone, Alfredo, Tournigand, Christophe, Kabbinavar, Fairooz F., Heinemann, Volker, Van Cutsem, Eric, Bokemeyer, Carsten, Buyse, Marc, Sargent, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482837/
https://ncbi.nlm.nih.gov/pubmed/25385741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.56.5887
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