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Structure-Function Analysis of PPP1R3D, a Protein Phosphatase 1 Targeting Subunit, Reveals a Binding Motif for 14-3-3 Proteins which Regulates its Glycogenic Properties

Protein phosphatase 1 (PP1) is one of the major protein phosphatases in eukaryotic cells. It plays a key role in regulating glycogen synthesis, by dephosphorylating crucial enzymes involved in glycogen homeostasis such as glycogen synthase (GS) and glycogen phosphorylase (GP). To play this role, PP1...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rubio-Villena, Carla, Sanz, Pascual, Garcia-Gimeno, Maria Adelaida
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482762/
https://ncbi.nlm.nih.gov/pubmed/26114292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131476
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