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Serum- and Glucocorticoid-Inducible Kinase-1 (SGK-1) Plays a Role in Membrane Trafficking in Caenorhabditis elegans

The mammalian serum- and glucocorticoid-inducible kinase SGK1 regulates the endocytosis of ion channels. Here we report that in C. elegans sgk-1 null mutants, GFP-tagged MIG-14/Wntless, the sorting receptor of Wnt, failed to localize to the basolateral membrane of intestinal cells; instead, it was m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhu, Ming, Wu, Gang, Li, Yu-Xin, Stevens, Julia Kathrin, Fan, Chao-Xuan, Spang, Anne, Dong, Meng-Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482599/
https://ncbi.nlm.nih.gov/pubmed/26115433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130778
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