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rMCP-2, the Major Rat Mucosal Mast Cell Protease, an Analysis of Its Extended Cleavage Specificity and Its Potential Role in Regulating Intestinal Permeability by the Cleavage of Cell Adhesion and Junction Proteins

Mast cells of the rat intestinal mucosa express three chymotryptic enzymes named rMCP-2, -3 and 4. rMCP-2, the most abundant of these enzymes, has been shown to increase the permeability of the intestinal epithelium, most likely by cleavage of cell adhesion and junction proteins and thereby play a r...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fu, Zhirong, Thorpe, Michael, Hellman, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482586/
https://ncbi.nlm.nih.gov/pubmed/26114959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131720
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