Genotypic Diversity Is Associated with Clinical Outcome and Phenotype in Cryptococcal Meningitis across Southern Africa

Cryptococcal meningitis is a major cause of mortality throughout the developing world, yet little is known about the genetic markers underlying Cryptococcal virulence and patient outcome. We studied a cohort of 230 Cryptococcus neoformans (Cn) isolates from HIV-positive South African clinical trial...

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Veröffentlicht in:PLoS Negl Trop Dis
Hauptverfasser: Beale, Mathew A., Sabiiti, Wilber, Robertson, Emma J., Fuentes-Cabrejo, Karen M., O’Hanlon, Simon J., Jarvis, Joseph N., Loyse, Angela, Meintjes, Graeme, Harrison, Thomas S., May, Robin C., Fisher, Matthew C., Bicanic, Tihana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482434/
https://ncbi.nlm.nih.gov/pubmed/26110902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003847
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