Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease

Eitemau Tebyg

• Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo
  gan: Edwards, Claire M., et al.
  Cyhoeddwyd: (2009)
• Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo
  gan: Edwards, Claire M., et al.
  Cyhoeddwyd: (2008)
• The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo
  gan: Pennisi, Angela, et al.
  Cyhoeddwyd: (2009)
• Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging
  gan: Oyajobi, Babatunde O., et al.
  Cyhoeddwyd: (2007)
• Synthesis of a Bone-Targeted Bortezomib with In Vivo Anti-Myeloma Effects in Mice
  gan: Hua Wang, et al.
  Cyhoeddwyd: (2018-09-01)