Xilonix, a Novel True Human Antibody Targeting the Inflammatory Cytokine Interleukin-1 alpha, in Non-Small Cell Lung Cancer

BACKGROUND: Advanced non-small cell lung cancer (NSCLC) patients were treated as part of a Phase I dose escalation and expansion study evaluating a true human monoclonal antibody targeting IL-1α (Xilonix), which is intended to modulate the malignant phenotype—inhibiting tumor growth, spread and offe...

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Pubblicato in:Invest New Drugs
Autori principali: Hong, David S., Janku, Filip, Naing, Aung, Falchook, Gerald S., Piha-Paul, Sarina, Wheler, Jennifer J., Fu, Siqing, Tsimberidou, Apostolia M., Stecher, Michael, Mohanty, Prasant, Simard, John, Kurzrock, Razelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482235/
https://ncbi.nlm.nih.gov/pubmed/25822109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-015-0226-6
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