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A Possible Role of Acrolein in Diabetic Retinopathy: Involvement of a VEGF/TGFβ Signaling Pathway of the Retinal Pigment Epithelium in Hyperglycemia

PURPOSE: Acrolein has been implicated in retinal pigment epithelium (RPE) cell death, and has been associated with diabetic retinopathy. Our purpose was to investigate the potential effect of high glucose in influencing acrolein-mediated RPE cytokine production and cell death. We investigated the in...

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Bibliografiska uppgifter
I publikationen:Curr Eye Res
Huvudupphovsmän: Grigsby, Jeffery, Betts, Brandi, Vidro-Kotchan, Eileen, Culbert, Richard, Tsin, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482234/
https://ncbi.nlm.nih.gov/pubmed/22906079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02713683.2012.713152
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