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A Possible Role of Acrolein in Diabetic Retinopathy: Involvement of a VEGF/TGFβ Signaling Pathway of the Retinal Pigment Epithelium in Hyperglycemia

PURPOSE: Acrolein has been implicated in retinal pigment epithelium (RPE) cell death, and has been associated with diabetic retinopathy. Our purpose was to investigate the potential effect of high glucose in influencing acrolein-mediated RPE cytokine production and cell death. We investigated the in...

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Detalhes bibliográficos
Publicado no:Curr Eye Res
Main Authors: Grigsby, Jeffery, Betts, Brandi, Vidro-Kotchan, Eileen, Culbert, Richard, Tsin, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482234/
https://ncbi.nlm.nih.gov/pubmed/22906079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02713683.2012.713152
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