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Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression

BACKGROUND: Secretory expression of valuable proteins by B. subtilis and its related species has attracted intensive work over the past three decades. Although very high yields can be achieved with homologous proteins, production of heterologous proteins by B. subtilis is unfortunately not the strai...

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Bibliografski detalji
Izdano u:Microb Cell Fact
Glavni autori: Chen, Jingqi, Fu, Gang, Gai, Yuanming, Zheng, Ping, Zhang, Dawei, Wen, Jianping
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482152/
https://ncbi.nlm.nih.gov/pubmed/26112883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0282-9
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