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Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression

BACKGROUND: Secretory expression of valuable proteins by B. subtilis and its related species has attracted intensive work over the past three decades. Although very high yields can be achieved with homologous proteins, production of heterologous proteins by B. subtilis is unfortunately not the strai...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Microb Cell Fact
Main Authors: Chen, Jingqi, Fu, Gang, Gai, Yuanming, Zheng, Ping, Zhang, Dawei, Wen, Jianping
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482152/
https://ncbi.nlm.nih.gov/pubmed/26112883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0282-9
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