Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression

BACKGROUND: Secretory expression of valuable proteins by B. subtilis and its related species has attracted intensive work over the past three decades. Although very high yields can be achieved with homologous proteins, production of heterologous proteins by B. subtilis is unfortunately not the strai...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Microb Cell Fact
Prif Awduron: Chen, Jingqi, Fu, Gang, Gai, Yuanming, Zheng, Ping, Zhang, Dawei, Wen, Jianping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482152/
https://ncbi.nlm.nih.gov/pubmed/26112883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0282-9
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