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A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice

Normal fusion of developing eyelids requires coordination of inductive signals from the eyelid mesenchyme with migration of the periderm cell layer and constriction of the eyelids across the eye. Failure of this process results in an eyelids open at birth (EOB) phenotype in mice. We have identified...

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Bibliografske podrobnosti
izdano v:Mamm Genome
Main Authors: Curtain, Michelle, Heffner, Caleb S., Maddox, Dennis M., Gudis, Polyxeni, Donahue, Leah Rae, Murray, Stephen A.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482110/
https://ncbi.nlm.nih.gov/pubmed/25673119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-015-9557-z
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