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CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes
In metazoan cells, spliced mRNAs are marked by the exon junction complex (EJC), a multi-protein complex that serves as a key regulator of post-transcriptional mRNA metabolism. Deposition of EJCs on mRNA is intimately linked to the splicing process. The spliceosomal protein CWC22 directly binds the c...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482076/ https://ncbi.nlm.nih.gov/pubmed/25870412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv320 |
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