AKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage

Post-translational modifications of core histones affect various cellular processes, primarily through transcription. However, their relationship with the termination of transcription has remained largely unknown. In this study, we show that DNA damage-activated AKT phosphorylates threonine 45 of co...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Lee, Jong-Hyuk, Kang, Byung-Hee, Jang, Hyonchol, Kim, Tae Wan, Choi, Jinmi, Kwak, Sojung, Han, Jungwon, Cho, Eun-Jung, Youn, Hong-Duk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482061/
https://ncbi.nlm.nih.gov/pubmed/25813038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv176
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