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NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7

BACKGROUND: Although matrix metalloproteinase (MMP)-7 expression is correlated with increased metastatic potential in human colon cancer cells, the underlying molecular mechanism of invasive phenotype remains unknown. In the current study, we investigated the regulatory effects of membrane NADPH oxi...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Banskota, Suhrid, Regmi, Sushil C., Kim, Jung-Ae
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482031/
https://ncbi.nlm.nih.gov/pubmed/26116564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0379-0
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