Normalization and noise reduction for single cell RNA-seq experiments

A major roadblock towards accurate interpretation of single cell RNA-seq data is large technical noise resulted from small amount of input materials. The existing methods mainly aim to find differentially expressed genes rather than directly de-noise the single cell data. We present here a powerful...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Ding, Bo, Zheng, Lina, Zhu, Yun, Li, Nan, Jia, Haiyang, Ai, Rizi, Wildberg, Andre, Wang, Wei
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Applications Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481848/
https://ncbi.nlm.nih.gov/pubmed/25717193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv122
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