Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains

Human HtrA3 protease, which induces mitochondria-mediated apoptosis, can be a tumor suppressor and a potential therapeutic target in the treatment of cancer. However, there is little information about its structure and biochemical properties. HtrA3 is composed of an N-terminal domain not required fo...

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Veröffentlicht in:PLoS One
Hauptverfasser: Glaza, Przemyslaw, Osipiuk, Jerzy, Wenta, Tomasz, Zurawa-Janicka, Dorota, Jarzab, Miroslaw, Lesner, Adam, Banecki, Bogdan, Skorko-Glonek, Joanna, Joachimiak, Andrzej, Lipinska, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481513/
https://ncbi.nlm.nih.gov/pubmed/26110759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131142
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