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Insulin-like factor regulates neural induction through an IGF1 receptor-independent mechanism

Insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF1R) signalling is required for normal embryonic growth and development. Previous reports indicated that the IGF/IGF1R/MAPK pathway contributes to neural induction and the IGF/IGF1R/PI3K/Akt pathway to eye development. Here, we repor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Haramoto, Yoshikazu, Takahashi, Shuji, Oshima, Tomomi, Onuma, Yasuko, Ito, Yuzuru, Asashima, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481404/
https://ncbi.nlm.nih.gov/pubmed/26112133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11603
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