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Calreticulin and Arginylated Calreticulin Have Different Susceptibilities to Proteasomal Degradation

Post-translational arginylation has been suggested to target proteins for proteasomal degradation. The degradation mechanism for arginylated calreticulin (R-CRT) localized in the cytoplasm is unknown. To evaluate the effect of arginylation on CRT stability, we examined the metabolic fates and degrad...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Goitea, Victor E., Hallak, Marta E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481237/
https://ncbi.nlm.nih.gov/pubmed/25969538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.626127
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