Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION

The identity of calcium channels in the thyroid is unclear. In human follicular thyroid ML-1 cancer cells, sphingolipid sphingosine 1-phosphate (S1P), through S1P receptors 1 and 3 (S1P(1)/S1P(3)), and VEGF receptor 2 (VEGFR2) stimulates migration. We show that human thyroid cells express several fo...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Asghar, Muhammad Yasir, Magnusson, Melissa, Kemppainen, Kati, Sukumaran, Pramod, Löf, Christoffer, Pulli, Ilari, Kalhori, Veronica, Törnquist, Kid
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481213/
https://ncbi.nlm.nih.gov/pubmed/25971967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.643668
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