Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α)

Resveratrol (RSV) and SRT1720 (SRT) elicit beneficial metabolic effects and are postulated to ameliorate obesity and related metabolic complications. The co-activator, peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α), has emerged as a major downstream effector responsible for me...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Svensson, Kristoffer, Schnyder, Svenia, Albert, Verena, Cardel, Bettina, Quagliata, Luca, Terracciano, Luigi M., Handschin, Christoph
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481209/
https://ncbi.nlm.nih.gov/pubmed/25987562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.590653
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