Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS

Urokinase plasminogen activator (uPA) converts plasminogen to plasmin, resulting in a proteolytic cascade that has been implicated in tissue destruction during inflammation. Periodontitis is a highly prevalent chronic inflammatory disease characterized by destruction of the tissue and bone that supp...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Fleetwood, Andrew J., O'Brien-Simpson, Neil M., Veith, Paul D., Lam, Roselind S., Achuthan, Adrian, Cook, Andrew D., Singleton, William, Lund, Ida K., Reynolds, Eric C., Hamilton, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481207/
https://ncbi.nlm.nih.gov/pubmed/25979345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645572
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