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Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS
Urokinase plasminogen activator (uPA) converts plasminogen to plasmin, resulting in a proteolytic cascade that has been implicated in tissue destruction during inflammation. Periodontitis is a highly prevalent chronic inflammatory disease characterized by destruction of the tissue and bone that supp...
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Foilsithe in: | J Biol Chem |
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Main Authors: | , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
American Society for Biochemistry and Molecular Biology
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4481207/ https://ncbi.nlm.nih.gov/pubmed/25979345 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645572 |
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