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5-Thiocyanato-2′-deoxyuridine as a Possible Radiosensitizer: Electron-Induced Formation of Uracil-C5-Thiyl Radical and Its Dimerization

In this work, we have synthesized 5-thiocyanato-2′-deoxyuridine (SCNdU) along with the C6-deuterated nucleobase 5-thiocyanatouracil (6-D-SCNU) and studied their reactions with radiation-produced electrons. ESR spectra in γ-irradiated nitrogen-saturated frozen homogeneous solutions (7.5 M LiCl in H(2...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Zdrowowicz, Magdalena, Chomicz, Lidia, Żyndul, Michał, Wityk, Paweł, Rak, Janusz, Wiegand, Tyler J., Hanson, Cameron G., Adhikary, Amitava, Sevilla, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481187/
https://ncbi.nlm.nih.gov/pubmed/26059609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cp02081f
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