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Identification of an Auxiliary Leader Peptide-Binding Protein Required for Azoline Formation in Ribosomal Natural Products

Thiazole/oxazole-modified microcins (TOMMs) are a class of posttranslationally modified peptide natural products bearing azole and azoline heterocycles. The first step in heterocycle formation is carried out by a two component cyclodehydratase comprised of an E1 ubiquitin-activating and a YcaO super...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Dunbar, Kyle L., Tietz, Jonathan I., Cox, Courtney L., Burkhart, Brandon J., Mitchell, Douglas A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481143/
https://ncbi.nlm.nih.gov/pubmed/26024319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04682
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