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In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4(+)CD25(-) T Cells Using an Hsp70 Peptide

Therapeutic peptides that target antigen-specific regulatory T cells (Tregs) can suppress experimental autoimmune diseases. The heat shock protein (Hsp) 70, with its expression elevated in inflamed tissue, is a suitable candidate antigen because administration of both bacterial and mouse Hsp70 pepti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van Herwijnen, Martijn J. C., van der Zee, Ruurd, van Eden, Willem, Broere, Femke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481099/
https://ncbi.nlm.nih.gov/pubmed/26107957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128373
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