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In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4(+)CD25(-) T Cells Using an Hsp70 Peptide

Therapeutic peptides that target antigen-specific regulatory T cells (Tregs) can suppress experimental autoimmune diseases. The heat shock protein (Hsp) 70, with its expression elevated in inflamed tissue, is a suitable candidate antigen because administration of both bacterial and mouse Hsp70 pepti...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: van Herwijnen, Martijn J. C., van der Zee, Ruurd, van Eden, Willem, Broere, Femke
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481099/
https://ncbi.nlm.nih.gov/pubmed/26107957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128373
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