Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients

Elevated systolic pulmonary artery pressure (s-PAP, ≥35 mmHg) serves as an independent predictor of mortality in hemodialysis (HD) and diabetic (DM) patients. A polymorphism in the antioxidant Haptoglobin (Hp) gene has been shown to regulate the bioavailability of nitric oxide (NO), a major mediator...

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Bibliographic Details
Published in:J Diabetes Res
Main Authors: Dahan, Inbal, Farber, Evgeny, Thauho, Nadia, Nakhoul, Nakhoul, Francis, Adi, Awawde, Mohamad, Levy, Andrew P., Kim-Shapiro, Daniel B., Basu, Swati, Nakhoul, Farid
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
Subjects:
Clinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481085/
https://ncbi.nlm.nih.gov/pubmed/26171400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/613860
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