Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway

PGC-1α, a major metabolic regulator of gluconeogenesis and lipogenesis, is strongly induced to coactivate Hepatitis B virus (HBV) gene expression in the liver of fasting mice. We found that 8-Br-cAMP and glucocorticoids synergistically induce PGC-1α and its downstream targets, including PEPCK and G6...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jhuang, Hong-Jhih, Hsu, Wei-Hsiang, Lin, Kuan-Ting, Hsu, Shih-Lan, Wang, Feng-Sheng, Chou, Chen-Kung, Lee, Kuen-Haur, Tsou, Ann-Ping, Lai, Jin-Mei, Yeh, Sheau-Farn, Huang, Chi-Ying F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480716/
https://ncbi.nlm.nih.gov/pubmed/25762623
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