miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells

VitaminD3 signaling is involved in inhibiting the development and progression of gastric cancer (GC), while the active vitamin D metabolite 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)(2)D(3))-mediated gene regulatory mechanisms in GC remain unclear. We found that miR-145 is induced by 1,25(OH)(2)D(3) i...

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Publicat a:Oncotarget
Autors principals: Chang, Su'e, Gao, Ling, Yang, Yang, Tong, Dongdong, Guo, Bo, Liu, Liying, Li, Zongfang, Song, Tusheng, Huang, Chen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480708/
https://ncbi.nlm.nih.gov/pubmed/25762621
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