Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation

BACKGROUND: Differentiation of metazoan cells requires execution of different gene expression programs but recent single-cell transcriptome profiling has revealed considerable variation within cells of seeming identical phenotype. This brings into question the relationship between transcriptome stat...

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Gepubliceerd in:Genome Biol
Hoofdauteurs: Dueck, Hannah, Khaladkar, Mugdha, Kim, Tae Kyung, Spaethling, Jennifer M., Francis, Chantal, Suresh, Sangita, Fisher, Stephen A., Seale, Patrick, Beck, Sheryl G., Bartfai, Tamas, Kuhn, Bernhard, Eberwine, James, Kim, Junhyong
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480509/
https://ncbi.nlm.nih.gov/pubmed/26056000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0683-4
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