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Variation is function: Are single cell differences functionally important?: Testing the hypothesis that single cell variation is required for aggregate function

There is a growing appreciation of the extent of transcriptome variation across individual cells of the same cell type. While expression variation may be a byproduct of, for example, dynamic or homeostatic processes, here we consider whether single‐cell molecular variation per se might be crucial fo...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Dueck, Hannah, Eberwine, James, Kim, Junhyong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738397/
https://ncbi.nlm.nih.gov/pubmed/26625861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201500124
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