Exploring the role of drug-metabolising enzymes in antidepressant side effects

RATIONALE: Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly polymorphic nature of these enzymes has been linked to variability in antidepressant metabolism rates, leading to hope regarding the use of P450 genotyping to guide treatment. However, evidence that P45...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Hodgson, Karen, Tansey, Katherine E., Uher, Rudolf, Dernovšek, Mojca Zvezdana, Mors, Ole, Hauser, Joanna, Souery, Daniel, Maier, Wolfgang, Henigsberg, Neven, Rietschel, Marcella, Placentino, Anna, Craig, Ian W., Aitchison, Katherine J., Farmer, Anne E., Dobson, Richard J. B., McGuffin, Peter
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2015
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480333/
https://ncbi.nlm.nih.gov/pubmed/25761838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3898-x
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