Exploring the role of drug-metabolising enzymes in antidepressant side effects

RATIONALE: Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly polymorphic nature of these enzymes has been linked to variability in antidepressant metabolism rates, leading to hope regarding the use of P450 genotyping to guide treatment. However, evidence that P45...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Psychopharmacology (Berl)
Main Authors: Hodgson, Karen, Tansey, Katherine E., Uher, Rudolf, Dernovšek, Mojca Zvezdana, Mors, Ole, Hauser, Joanna, Souery, Daniel, Maier, Wolfgang, Henigsberg, Neven, Rietschel, Marcella, Placentino, Anna, Craig, Ian W., Aitchison, Katherine J., Farmer, Anne E., Dobson, Richard J. B., McGuffin, Peter
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2015
Teme:
Original Investigation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480333/
https://ncbi.nlm.nih.gov/pubmed/25761838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3898-x
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