Exploring the role of drug-metabolising enzymes in antidepressant side effects

RATIONALE: Cytochrome P450 enzymes are important in the metabolism of antidepressants. The highly polymorphic nature of these enzymes has been linked to variability in antidepressant metabolism rates, leading to hope regarding the use of P450 genotyping to guide treatment. However, evidence that P45...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Hodgson, Karen, Tansey, Katherine E., Uher, Rudolf, Dernovšek, Mojca Zvezdana, Mors, Ole, Hauser, Joanna, Souery, Daniel, Maier, Wolfgang, Henigsberg, Neven, Rietschel, Marcella, Placentino, Anna, Craig, Ian W., Aitchison, Katherine J., Farmer, Anne E., Dobson, Richard J. B., McGuffin, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480333/
https://ncbi.nlm.nih.gov/pubmed/25761838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3898-x
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