Prophylactic Edaravone Prevents Transient Hypoxic-Ischemic Brain Injury: Implications for Perioperative Neuroprotection

BACKGROUND AND PURPOSE: Hypoperfusion-induced thrombosis is an important mechanism for post-surgery stroke and cognitive decline, but there are no perioperative neuroprotectants to date. This study investigated whether prophylactic application of Edaravone, a free radical scavenger already used in t...

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Vydáno v:Stroke
Hlavní autoři: Sun, Yu-Yo, Li, Yikun, Wali, Bushra, Li, Yuancheng, Lee, Jolly, Heinmiller, Andrew, Abe, Koji, Stein, Donald G., Mao, Hui, Sayeed, Iqbal, Kuan, Chia-Yi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480193/
https://ncbi.nlm.nih.gov/pubmed/26060244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.009162
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