α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways

Urinary urgency and frequency are common in α-synucleinopathies such as Parkinson’s Disease, Lewy Body Dementia and Multiple System Atrophy. These symptoms cannot be managed with dopamine therapy, and their underlying pathophysiology is unclear. We show that in individuals with Parkinson’s Disease,...

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Bibliographic Details
Published in:Ann Neurol
Main Authors: VanderHorst, Veronique G., Samardzic, Tamara, Saper, Clifford B., Anderson, Matthew P., Nag, Sukriti, Schneider, Julie A., Bennett, David A., Buchman, Aron S.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480165/
https://ncbi.nlm.nih.gov/pubmed/25893830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24430
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