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α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways

Urinary urgency and frequency are common in α-synucleinopathies such as Parkinson’s Disease, Lewy Body Dementia and Multiple System Atrophy. These symptoms cannot be managed with dopamine therapy, and their underlying pathophysiology is unclear. We show that in individuals with Parkinson’s Disease,...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: VanderHorst, Veronique G., Samardzic, Tamara, Saper, Clifford B., Anderson, Matthew P., Nag, Sukriti, Schneider, Julie A., Bennett, David A., Buchman, Aron S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480165/
https://ncbi.nlm.nih.gov/pubmed/25893830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24430
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