Understanding paratyphoid infection: study protocol for the development of a human model of Salmonella enterica serovar Paratyphi A challenge in healthy adult volunteers

INTRODUCTION: This study will develop the first human challenge model of paratyphoid infection which may then be taken forward to evaluate paratyphoid vaccine candidates. Salmonella Paratyphi A is believed to cause a quarter of the estimated 20 million cases of enteric fever annually. Epidemiologica...

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Vydáno v:BMJ Open
Hlavní autoři: McCullagh, David, Dobinson, Hazel C, Darton, Thomas, Campbell, Danielle, Jones, Claire, Snape, Matthew, Stevens, Zoe, Plested, Emma, Voysey, Merryn, Kerridge, Simon, Martin, Laura B, Angus, Brian, Pollard, Andrew J
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2015
Témata:
Infectious Diseases
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480031/
https://ncbi.nlm.nih.gov/pubmed/26082464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-007481
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