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Nanopore sensing of individual transcription factors bound to DNA

Transcription factor (TF)-DNA interactions are the primary control point in regulation of gene expression. Characterization of these interactions is essential for understanding genetic regulation of biological systems and developing novel therapies to treat cellular malfunctions. Solid-state nanopor...

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Publicat a:Sci Rep
Autors principals: Squires, Allison, Atas, Evrim, Meller, Amit
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479991/
https://ncbi.nlm.nih.gov/pubmed/26109509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11643
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