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Nanopore sensing of individual transcription factors bound to DNA

Transcription factor (TF)-DNA interactions are the primary control point in regulation of gene expression. Characterization of these interactions is essential for understanding genetic regulation of biological systems and developing novel therapies to treat cellular malfunctions. Solid-state nanopor...

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Detalles Bibliográficos
Publicado en:Sci Rep
Autores principales: Squires, Allison, Atas, Evrim, Meller, Amit
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479991/
https://ncbi.nlm.nih.gov/pubmed/26109509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11643
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