Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways

The current study investigated the cytotoxic effect of 3-(5-chloro-2-hydroxybenzylideneamino)-2-(5-chloro-2-hydroxyphenyl)-2,3-dihydroquinazolin-41(H)-one (A) and 3-(5-nitro-2-hydroxybenzylideneamino)-2-(5-nitro-2-hydroxyphenyl)-2,3-dihydroquinazolin-4(1H)-one (B) on MCF-7, MDA-MB-231, MCF-10A and W...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zahedifard, Maryam, Lafta Faraj, Fadhil, Paydar, Mohammadjavad, Yeng Looi, Chung, Hajrezaei, Maryam, Hasanpourghadi, Mohadeseh, Kamalidehghan, Behnam, Abdul Majid, Nazia, Mohd Ali, Hapipah, Ameen Abdulla, Mahmood
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479988/
https://ncbi.nlm.nih.gov/pubmed/26108872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11544
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